evolocity.tl.residue_scores¶

evolocity.tl.residue_scores(adata, basis='onehot', scale=1.0, key='residue_scores', copy=False)¶

Score mutations by associated evolocity.

Requires running evo.tl.onehot_msa first.

Parameters

adata : Anndata: Annoated data matrix.
basis : str (default: ‘onehot’): Name of one-hot embedding
scale : float (default: 1.): Scale parameter of gaussian kernel for transition matrix.
key : str (default: ‘residue_scores’): Name at which to place scores.
copy : bool (default: False): Return a copy instead of writing to adata.

Returns